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Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.



Selected by Fiona Macleod

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley



Selected by Benjamin Dominik Maier

Flat clathrin lattices are linked to metastatic potential in colorectal cancer

Charlotte Cresens, Guillermo Solis-Fernandez, Astha Tiwari, et al.



Selected by Emily Chan

Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture

Clémentine Villeneuve, Ali Hashmi, Irene Ylivinkka, et al.



Selected by Sudeepa Nandi

Functional synapses between small cell lung cancer and glutamatergic neurons

Anna Schmitt, Vignesh Sakthivelu, Kristiano Ndoci, et al.



Selected by Jade Chan

Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

Johanna Lilja, Jasmin Kaivola, James R.W. Conway, et al.



Selected by Yvonne Xinyi Lim

Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.



Selected by Nate Mullin

Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration

Rituraj Marwaha, Simran Rawal, Purnati Khuntia, et al.



Selected by Jade Chan

MPS1 localizes to microtubule-attached kinetochores and actively promotes microtubule release

Daniel Hayward, Emile Roberts, Ulrike Gruneberg



Selected by Saanjbati Adhikari

Tissue confinement regulates cell growth and size in epithelia

John Devany, Martin J. Falk, Liam J. Holt, et al.



Selected by Nicolaes Hyun-Kee Min

The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination

Alejandra J.H. Cabrera, Barry M. Gumbiner, Young V. Kwon



Selected by Holly Smith

Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, et al.



Selected by Sagar Varankar

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